Following an invitation for the Army to establish a presence in Mali, registration was given on 29 November 2007. Work began under local leadership with oversight from Nigeria. In February 2008 officers were appointed. Mali was officially declared a separate region on 1 April 2010.
Unofficial work in Burkina Faso has been ongoing since 2012, with it being officially opened on 12 June 2018.
Lieut-Colonel Blaise Kombo - Regional Commander
Lieut-Colonel Evelyne Kombo - Regional President for Women's Ministries
Captain André Togo - Regional Secretary
Captain Nana Togo - Regional Secretary for Women's Ministries
Rue 360 Face Real de Bamako,
ACI 2000 Bamako,
Armée du Salut Quartier Général,
BP E 5249,
Tel:  72499071
In February 2021, the region launched the annual theme `Walking by Faith for a Strong and Stable Church' - this event included section officers and section directors for Women's Ministries orientation, officers councils, the commissioning of band leaders and a songster sergeant, and featured musicians and the regional timbrelists, testimonies and the enrolment of more than 100 senior and junior soldiers.
The region provided a food delivery service through its Newman feeding social programme to those in need in Commune IV, Bamako, under the patronage of the mayor and through the media coverage of ORTM, the national television network. More than 2,000 people benefitted from this project.
The Women's Ministries team led a junior league meeting under the theme `Time to be Holy'. Major Naty Dorcias Ahoyanganga (RPWM), supported by Captain Fatouma Nana Togo (RSWM), emphasised the importance of living a holy life every day.
In October, the new church building in Bobo Dioulasso, Burkina Faso, was inaugurated and consecrated, attended by the regional leadership. The Safe Return to Corps project, which involves sanitary materials to corps and outposts in order to help prevent the spread of COVID-19, was also launched, benefitting the Salvation Army work in Poessin, Loumbila, Ouagadougou and Bobo Dioulasso.
In December, the RPWM and RSWM, with the help of the Women's Ministries team, shared gifts and the light of Christmas through street-side ministry. The Women's Ministries team also led a biblical camp attended by 300 women and Niamana Conference Centre.
As part of its community development project, in January 2021 the region distributed school supplies to various corps and outposts to assist pupils who have not been able to return to school.
Officers - 10 Envoys - 20
Cadets - 3 Employees - 5
Corps - 8 Outposts - 17
Senior Soldiers - 784 Adherents - 191 Junior Soldiers - 405
Country included in the region: Mali and Burkina Faso
Language in which the gospel is preached: Bambara and French